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Regulatory T Cell Stability and Migration Are Dependent on mTOR

Romain Vallion1, Jordane Divoux1, Salomé Glauzy1

  • 1Centre d'Immunologie et des Maladies Infectieuses, Sorbonne Université, INSERM, CNRS, 75013 Paris, France.

Journal of Immunology (Baltimore, Md. : 1950)
|August 26, 2020
PubMed
Summary

Mechanistic target of rapamycin (mTOR) is crucial for regulatory T cell (Treg) function. Deleting mTOR in Tregs causes severe inflammation, highlighting its importance in immune tolerance and Treg stability.

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