Artificial intelligence for decision support in acute stroke - current roles and potential

The identification and treatment of patients with stroke is becoming increasingly complex as more treatment options become available and new relationships between disease features and treatment response are continually discovered. Consequently, clinicians must constantly learn new skills (such as clinical evaluations or image interpretation), stay up to date with the literature and incorporate advances into everyday practice. The use of artificial intelligence (AI) to support clinical decision making could reduce inter-rater variation in routine clinical practice and facilitate the extraction of vital information that could improve identification of patients with stroke, prediction of treatment responses and patient outcomes. Such support systems would be ideal for centres that deal with few patients with stroke or for regional hubs, and could assist informed discussions with the patients and their families. Moreover, the use of AI for image processing and interpretation in stroke could provide any clinician with an imaging assessment equivalent to that of an expert. However, any AI-based decision support system should allow for expert clinician interaction to enable identification of errors (for example, in automated image processing). In this Review, we discuss the increasing importance of imaging in stroke management before exploring the potential and pitfalls of AI-assisted treatment decision support in acute stroke.