Dynamics of an SIS network model with a periodic infection rate
Lei Zhang1,2, Maoxing Liu1,2, Qiang Hou2
1School of Big Data, North University of China, Taiyuan Shanxi, 030051, China.
Abstract:
Seasonal forcing and contact patterns are two key features of many disease dynamics that generate periodic patterns. Both features have not been ascertained deeply in the previous works. In this work, we develop and analyze a non-autonomous degree-based mean field network model within a Susceptible-Infected-Susceptible (SIS) framework. We assume that the disease transmission rate being periodic to study synergistic impacts of the periodic transmission and the heterogeneity of the contact network on the infection threshold and dynamics for seasonal diseases. We demonstrate both analytically and numerically that (1) the disease free equilibrium point is globally asymptotically stable if the basic reproduction number is less than one; and (2) there exists a unique global periodic solution that both susceptible and infected individuals coexist if the basic reproduction number is larger than one. We apply our framework to Scale-free contact networks for the simulation. Our results show that heterogeneity in the contact networks plays an important role in accelerating disease spreading and increasing the amplitude of the periodic steady state solution. These results confirm the need to address factors that create periodic patterns and contact patterns in seasonal disease when making policies to control an outbreak.
Insights
This study models seasonal disease spread using a Susceptible-Infected-Susceptible (SIS) framework. Network heterogeneity significantly impacts disease dynamics and outbreak control strategies.
Area of Science:
- Epidemiology
- Mathematical Biology
- Network Science
Background:
- Periodic patterns in disease dynamics are influenced by seasonal forcing and contact patterns.
- Previous research has not fully explored the interplay of these factors.
Purpose of the Study:
- To develop and analyze a non-autonomous, degree-based mean-field network model for seasonal diseases.
- To investigate the synergistic effects of periodic transmission rates and contact network heterogeneity on disease spread.
Main Methods:
- Utilized a Susceptible-Infected-Susceptible (SIS) framework with a periodic transmission rate.
- Employed a degree-based mean-field network model applied to scale-free networks.
- Conducted both analytical and numerical analyses.
Main Results:
- Established conditions for global asymptotic stability of the disease-free equilibrium (basic reproduction number < 1).
- Demonstrated the existence of a unique global periodic solution with coexisting susceptible and infected individuals (basic reproduction number > 1).
- Showed that contact network heterogeneity accelerates disease spread and increases the amplitude of periodic solutions.
Conclusions:
- Contact network structure is crucial for understanding and predicting seasonal disease dynamics.
- Effective disease control policies must consider both periodic transmission and contact network characteristics.
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