Intestinal ischemia secondary to Covid-19

Lamia Sabrina Khesrani1, Karima Chana2, Fatma Zohra Sadar3

  • 1Pediatric Surgery Département, CHU Mustapha, Algiers, Algeria.

Insights

A rare case of pediatric intestinal ischemia linked to COVID-19 infection is presented. This finding highlights a potential vascular complication, multisystem inflammatory syndrome in children (MIS-C), associated with SARS-CoV-2 in pediatric patients.

Area of Science:

  • Pediatric Gastroenterology
  • Infectious Diseases
  • Vascular Inflammation

Background:

  • COVID-19 affects children, often asymptomatically.
  • A concern exists regarding Kawasaki disease-like vascular inflammatory conditions in pediatric COVID-19 cases.

Observation:

  • A 9-year-old girl with aplastic anemia presented with shock, neurological, and skin symptoms.
  • Surgical exploration revealed ischemic bowel lesions, with a healthy appendix.
  • COVID-19 infection was confirmed via RT-PCR.

Findings:

  • The case demonstrates a combination of COVID-19 infection and intestinal ischemia in a child.
  • Intestinal vasculitis is identified as a potential component of multisystem inflammatory syndrome in children (MIS-C) related to COVID-19.

Implications:

  • This case underscores the importance of considering intestinal vasculitis in pediatric COVID-19 patients presenting with abdominal symptoms.
  • Highlights a novel presentation of COVID-19 complications in children, emphasizing the need for further research into MIS-C and its vascular manifestations.

Related Concept Videos

Acute Coronary Syndrome II: Pathophysiology and Clinical Manifestations01:19

Acute Coronary Syndrome II: Pathophysiology and Clinical Manifestations

The pathophysiology of Acute Coronary Syndrome [ACD] involves several key processes:The main underlying cause of ACD is atherosclerosis, a chronic inflammatory disease characterized by the buildup of lipid-laden plaques within the coronary arteries.As the atherosclerotic plaque grows in the coronary artery, it may become unstable due to the formation of a lipid-rich core and a thin fibrous cap. Inflammatory cells within the plaque, such as macrophages, secrete enzymes that degrade the...
249
Acute Coronary Syndrome I: Introduction01:30

Acute Coronary Syndrome I: Introduction

Acute Coronary Syndrome (ACS) encompasses a spectrum of heart conditions caused by sudden obstruction of coronary arteries, typically resulting from the rupture of an atherosclerotic plaque and subsequent thrombus (blood clot) formation. This obstruction can lead to partial or complete blockage of blood flow, causing varying degrees of myocardial ischemia or infarction.ACS includes the following clinical entities:Unstable Angina (UA)Non-ST-Elevation Myocardial Infarction (NSTEMI)ST-Elevation...
475
Ischemic Heart Disease: Overview01:17

Ischemic Heart Disease: Overview

Ischemic heart disease occurs when the heart's blood supply dwindles, causing an ominous lack of oxygen and nutrients. This deficiency, stemming from reduced or obstructed blood flow, spells danger, leading to heart muscle damage and dysfunction.
Atherosclerosis, the primary malefactor, orchestrates this dangerous condition. It manifests as the accumulation of fatty deposits, akin to insidious plaques, within arterial walls. As time elapses, these plaques metamorphose, hardening and...
2.6K
Endocarditis II: Clinical Features of Infective Endocarditis01:25

Endocarditis II: Clinical Features of Infective Endocarditis

Endocarditis can present various clinical features depending on the causative organism and the patient's underlying health conditions. Initially, the clinical features of infective endocarditis develop gradually, presenting with nonspecific symptoms that can be easily mistaken for other illnesses.General SymptomsEarly symptoms of infective endocarditis are fever, chills, weakness, malaise, fatigue, and weight loss. These symptoms reflect the systemic nature of the infection and the body's...
240
Myocarditis III: Medical Management01:14

Myocarditis III: Medical Management

Myocarditis: Comprehensive Medical ManagementMyocarditis, the heart muscle inflammation, requires a comprehensive medical management strategy that addresses the underlying cause, provides supportive care, manages symptoms, and reduces cardiac workload.Infections and Autoimmune CausesAdminister appropriate antimicrobial therapy when an infectious agent causes myocarditis. For instance, penicillin treats infections caused by Group A Streptococcus. In cases where autoimmune processes are...
95
Acute Coronary Syndrome IV: Interprofessional Care01:28

Acute Coronary Syndrome IV: Interprofessional Care

IntroductionThe management of Acute Coronary Syndrome (ACS) aims to minimize myocardial damage, preserve myocardial function, and prevent complications.Initial ManagementInpatient management involves continuous cardiac monitoring, preferably in an ICU, focusing on blood pressure, serum sodium, potassium, and creatinine levels, and urine output. Ongoing pharmacologic management is crucial for stabilizing the patient.Supplemental Oxygen: Administer supplemental oxygen if oxygen saturation is...
134