Related Experiment Video
Updated: Dec 11, 2025

Quantifying the Binding Interactions Between CuII and Peptide Residues in the Presence and Absence of Chromophores
Published on: April 5, 2022
A hemicyanine-based "turn-on" fluorescent probe for the selective detection of Cu2+ ions and imaging in living cells
Bai Li1, Jiejian Kou, Huihui Mei
1Henan Engineering Research Center of Industrial Recirculating Water Treatment, College of Chemistry and Chemical Engineering, Henan University, Kaifeng, Henan 475004, P. R. China. xukx@henu.edu.cn.
Abstract:
A novel hemicyanine-based fluorescent probe was developed for the fast, selective, and reversible detection of Cu2+ ions with "turn-on" fluorescence response in the aqueous solution. The sensing mode was demonstrated through fluorescence, UV-vis, HRMS, 1H NMR, and DFT calculations. The probe was successfully used for the imaging of Cu2+ ions in living cells.

