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Updated: Dec 11, 2025

Urinary Bladder Distention Evoked Visceromotor Responses as a Model for Bladder Pain in Mice
Published on: April 27, 2014
[Interstitial cystitis/bladder pain syndrome (IC/BPS)]
1Klinik für Urologie, Andrologie und Kinderurologie, Interdisziplinäres Kontinenz- und Beckenbodenzentrum Weiden, Zentrum für Interstitielle Zystitis (IC) und Beckenschmerz, Klinikum Weiden/Kliniken Nordoberpfalz AG, Söllnerstraße 16, 92637, Weiden, Deutschland. Th.B@gmx.de.
Abstract:
As an orphan disease interstitial cystitis/bladder pain syndrome (IC/BPS) is a frequently underdiagnosed and inadequately treated disease of the urinary bladder, often after years of symptoms. Caused by an unknown etiology, a high variability of symptoms, a lack of biomarkers and a gradual onset, IC/BPS is a diagnosis by exclusion and poses a special challenge to doctors and patients. In addition to conventional and complementary medical treatment, oral medication, intravesical and transurethral procedures are available as treatment options. Due to the invasiveness or irreversibility, however, interventional surgical procedures should only be used after careful consideration or as a last resort. In order to find a suitable individualized treatment, a classification of the patients according to the severity and type of symptoms can be advantageous.
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