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Updated: Dec 11, 2025

Megakaryocyte Differentiation and Platelet Formation from Human Cord Blood-derived CD34+ Cells
Published on: December 27, 2017
Biotech-Educated Platelets: Beyond Tissue Regeneration 2.0
Sheila Siqueira Andrade1, Alessandra Valéria de Sousa Faria2,3, Manoel João Batista C Girão4
1PlateInnove Biotechnology, Piracicaba, SP 13414-018, Brazil.
Abstract:
The increasing discoveries regarding the biology and functions of platelets in the last decade undoubtedly show that these cells are one of the most biotechnological human cells. This review summarizes new advances in platelet biology, functions, and new concepts of biotech-educated platelets that connect advanced biomimetic science to platelet-based additive manufacturing for tissue regeneration. As highly responsive and secretory cells, platelets could be explored to develop solutions that alter injured microenvironments through platelet-based synthetic biomaterials with instructive extracellular cues for morphogenesis in tissue engineering beyond tissue regeneration 2.0.
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