Peripapillary pachychoroid neovasculopathy: A novel entity

Area of Science:

• Ophthalmology
• Medical Imaging
• Pathology

Background:

• Pachychoroid disease spectrum is a group of conditions characterized by choroidal thickening.
• Peripapillary pachychoroid syndrome is a recently described variant.
• Understanding its pathogenic mechanisms and association with neovascularization is crucial.

Observation:

• A 51-year-old woman presented with macular pigmentary changes.
• Spectral-domain optical coherence tomography revealed pigment epithelium detachment and pachyvessels.
• Optical coherence tomography angiography demonstrated extensive neovascularization.

Findings:

• Diagnosis of peripapillary pachychoroid neovasculopathy was established.
• Indocyanine green angiography confirmed pachyvessels and choroidal hyper-permeability.
• Intravitreal aflibercept treatment led to favorable visual and anatomical outcomes.

Implications:

• This case contributes to defining peripapillary pachychoroid neovasculopathy as a distinct entity.
• It enhances comprehension of choroidal neovascularization pathogenesis in pachychoroid disorders.
• It highlights effective treatment strategies for this condition.