The Effect of Preoperative Nutrition on Postoperative CRP and Albumin Levels in Patients Undergoing Laparoscopic...

The purpose of this study was to investigate the effect of preoperative oral carbohydrate on postoperative serum C-reactive protein (CRP) and albumin levels in patients laparoscopic surgery.

This is an experimental study with intervention and control groups.

Sixty-six patients who underwent elective laparoscopic cholecystectomy were included (intervention, n = 33; control, n = 33). The patients in the intervention group were given 400 mL of oral liquid carbohydrate 2 hours before surgery. Blood samples were collected from the two groups with serum CRP and albumin levels measured 2 hours before surgery and 24 hours postoperatively.

CRP levels in the intervention group 2 hours before surgery and 24 hours postoperatively were higher than the control group (P = .028; P = .014, respectively). CRP levels of the patients in the intervention group 24 hours postoperatively (26.98 ± 18.60 mg/L) were higher than the preoperative level (9.37 ± 15.68 mg/L) (P < .001). The CRP level of the patients in the control group 24 hours postoperatively (16.24 ± 16.01 mg/L) was higher than the preoperative level (3.11 ± 3.12 mg/L) (P < .001). There was no difference between the serum albumin levels of the patients in the intervention and control groups measured 24 hours postoperatively (P = .103).

We determined that 400 mL oral liquid carbohydrate given preoperatively had no anabolic effect on serum CRP and albumin levels.