Related Experiment Video
Updated: Dec 11, 2025

Ultrasound Assessment of Endothelial-Dependent Flow-Mediated Vasodilation of the Brachial Artery in Clinical Research
Published on: October 22, 2014
Gender Differences in Healthy Lifestyle Adherence Following Percutaneous Coronary Intervention for Coronary Artery
Sheneli Perera1, Anum Aslam1, Julia Stehli2
1Department of Medicine, Monash University, Melbourne, Vic, Australia.
Insights
Women treated for coronary artery disease (CAD) after percutaneous coronary intervention (PCI) show lower adherence to healthy lifestyles, particularly physical activity and cardiac rehabilitation. These findings highlight targets for gender-specific secondary prevention strategies.
Area of Science:
- Cardiovascular Medicine
- Public Health
- Gender Studies
Background:
- Coronary artery disease (CAD) is a primary cause of mortality among Australian women.
- Percutaneous coronary intervention (PCI) is a common treatment for CAD.
- Understanding gender differences in lifestyle adherence post-PCI is crucial for effective secondary prevention.
Purpose of the Study:
- To investigate gender-specific differences in healthy lifestyle adherence among patients who underwent PCI for CAD.
- To identify key areas where women may require targeted interventions for secondary prevention.
Main Methods:
- Prospective recruitment of consecutive patients from three Australian institutions between 2016 and 2017.
- Primary endpoint: healthy lifestyle adherence (heart-healthy diet, physical activity, non-smoking) at 1-year follow-up.
- Secondary endpoints: cardiac rehabilitation attendance, medication use, and lipid levels.
Main Results:
- Overall, 56% of participants adhered to all three lifestyle measures, with no significant gender difference.
- Women were less likely than men to be physically active (61.5% vs. 78.2%), attend cardiac rehabilitation (58.2% vs. 66.4%), and use statin therapy (85.4% vs. 94.7%).
- Female gender independently predicted physical inactivity (OR 2.41).
Conclusions:
- Significant gender disparities exist in secondary prevention adherence post-PCI for CAD.
- Women demonstrate lower rates of physical activity, cardiac rehabilitation attendance, and statin use compared to men.
- These differences underscore the need for gender-tailored secondary prevention programs to improve cardiovascular health outcomes in women.
Background:
Coronary artery disease (CAD) is the leading cause of mortality in Australian women. We identified gender differences in healthy lifestyle adherence in patients treated with percutaneous coronary intervention (PCI) for CAD.
Methods:
Consecutive patients were prospectively recruited from three Australian institutions (2016-2017). The primary endpoint at 1 year follow-up was healthy lifestyle adherence defined as 3/3 of: a heart-healthy diet, being physically active and not smoking. Secondary endpoints included cardiac rehabilitation attendance, medication use and lipid levels.
Results:
From 729 participants (n=192, 26.3% women) 56% were adherent to all three lifestyle measures with no gender difference overall. Compared to men, women were less likely to smoke (7.7% versus 12.2%, p<0.001) to be physically active (61.5% versus 78.2%; p<0.0001), attend cardiac rehabilitation (58.2% versus 66.4%; p<0.045), and take statin therapy (85.4% versus 94.7%; p<0.0001). Female gender independently predicted physical inactivity (OR 2.41, 95% CI 1.57-3.68, p<0.001).
Conclusion:
Important gender differences exist in patients treated with PCI for CAD, namely, significant lower physical activity, cardiac rehabilitation attendance and statin use in women. These all represent key targets for gender-specific secondary prevention interventions.
More Related Videos
04:24A Novel Digital Platform for a Monitored Home-based Cardiac Rehabilitation Program
Published on: April 19, 2019
05:41Left Anterior Descending Coronary Artery Ligation for Ischemia-Reperfusion Research: Model Improvement via Technical Modifications and Quality Control
Published on: December 16, 2022
Related Concept Videos
Coronary Artery Disease V: Interprofessional Care
Coronary Artery Disease IV: Preventive Measures
Acute Coronary Syndrome IV: Interprofessional Care
Peripheral Artery Disease III: Interprofessional Care
Atherosclerosis III: Management
Coronary Artery Disease I: Introduction