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Updated: Dec 10, 2025

Simultaneous Assessment of Kinship, Division Number, and Phenotype via Flow Cytometry for Hematopoietic Stem and Progenitor Cells
Published on: March 24, 2023
IBDkin: fast estimation of kinship coefficients from identity by descent segments
Ying Zhou1, Sharon R Browning1, Brian L Browning1,2
1Department of Biostatistics.
Motivation:
Estimation of pairwise kinship coefficients in large datasets is computationally challenging because the number of related individuals increases quadratically with sample size.
Results:
We present IBDkin, a software package written in C for estimating kinship coefficients from identity by descent (IBD) segments. We use IBDkin to estimate kinship coefficients for 7.95 billion pairs of individuals in the UK Biobank who share at least one detected IBD segment with length ≥ 4 cM.
Availability And Implementation:
https://github.com/YingZhou001/IBDkin.
Supplementary Information:
Supplementary data are available at Bioinformatics online.
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