Characterization of a new permanent squamous carcinoma line from human lung B 109

A permanent squamous carcinoma cell line was established from human lung. The cells exhibit good growth characteristics in vitro and in nude mice. Many marker chromosomes were detected. Histological examination and electron micrographs of B109 revealed at least two morphologically different subpopulations. The presence of steroid receptors and tumor associated antigens defined by monoclonal antibodies is discussed with regard to previously published results.