Related Experiment Video
Updated: Dec 10, 2025

Study of Experimental Organ Donation Models for Lung Transplantation
Published on: March 15, 2024
Beyond the ticked box: organ donation decision-making under different registration systems
Esther Steenaart1, Rik Crutzen1, Nanne K de Vries1
1Department of Health Promotion, CAPHRI Maastricht University, Maastricht, The Netherlands.
Objective:
To explore how people experience organ donation decision-making under the conditions of an opt-in, opt-out or no-objection registration system.
Design:
A between-subjects experimental 3 × 2 design (registration system x preselection). Participants (N = 1312) were presented with a description of one of the three registration systems and went through a mock donor registration process. In half of the conditions, the default option of the system was visualized by a ticked box. After, participants answered questions about their perceived autonomy and perceived effective decision-making.
Main Outcome Measurements:
Perceived autonomy, perceived decision effectiveness and registration choice.
Results:
The preselected box did not impact any of the outcomes. Participants had higher perceived autonomy under the conditions of an opt-in system. There were no differences in effective decision-making across conditions. Registration choices did differ across conditions and educational levels. In the opt-in system, participants more often made an active decision. Lower-educated participants were more likely to choose to do nothing, while higher-educated people more often made an active decision, especially in the no-objection system.
Conclusion:
Where the opt-out system potentially leads to the highest number of donors, the opt-in system seems better in terms of preserving people's autonomy and motivating people to make an active decision.
More Related Videos
09:54Lung Rapid Recovery Procurement Combined with Abdominal Normothermic Regional Perfusion in Controlled Donation after Circulatory Death
Published on: August 15, 2022
06:40A High-Fidelity Porcine Model of Orthotopic Heart Transplantation Following Donation after Circulatory Death
Published on: June 6, 2025
Related Concept Videos
Kidney Transplant I: Introduction
Tissue Transplantation
The Biology of Tissue Transplantation
The biology of tissue transplantation hinges on the Major Histocompatibility Complex (MHC) molecules. These molecules...
Kidney Transplant II: Surgical Procedure
Ethical Dilemmas II
Bone Marrow Sampling and Transplants
The transplant begins with high doses of chemotherapy and radiation treatment, which aim to destroy...