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08:49
Cultivating a Three-dimensional Reconstructed Human Epidermis at a Large Scale
Published on: May 28, 2021
Developing a cosmetic series: Results from the ESSCA network, 2009-2018
Emma Horton1, Wolfgang Uter2, Johannes Geier3
1Department of Dermatology, Chapel Allerton Hospital, Leeds, UK.
Contact Dermatitis
|August 27, 2020
Summary
A new European cosmetic series was proposed using data from 2009-2018. This standardized series includes 30 key cosmetic allergens to improve contact allergy diagnosis across Europe.
Area of Science:
- Dermatology
- Allergology
- Cosmetic Science
Background:
- Significant variability exists in cosmetic allergen series used by European patch test centers.
- Lack of standardization hinders consistent diagnosis of cosmetic contact allergy.
Purpose of the Study:
- To establish a unified, evidence-based European cosmetic series for patch testing.
- To standardize the identification of relevant cosmetic contact allergens.
Main Methods:
- Analysis of European Surveillance System on Contact Allergies (ESSCA) data from 2009-2018.
- Inclusion of contact allergens with a prevalence exceeding 0.3% and deemed relevant.
- Exclusion or supplementation of rare or evolving cosmetic allergens.
Main Results:
- Prevalence data for 39 cosmetic contact allergens were compiled.
- Thirty allergens with >0.3% positive reactions form the proposed core European cosmetic series.
- Six allergens were excluded as irrelevant, and three were added to a supplementary series.
Conclusions:
- A potential European cosmetic series has been developed based on extensive data analysis.
- Ongoing evaluation is necessary due to evolving cosmetic ingredients and exposure patterns.
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