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Updated: Dec 10, 2025

Application of Deep Learning-Based Medical Image Segmentation via Orbital Computed Tomography
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Prediction of visual field from swept-source optical coherence tomography using deep learning algorithms.

Keunheung Park1,2, Jinmi Kim3, Sangyoon Kim4

  • 1Department of Ophthalmology, Pusan National University College of Medicine, Busan, South Korea.

Graefe'S Archive for Clinical and Experimental Ophthalmology = Albrecht Von Graefes Archiv Fur Klinische Und Experimentelle Ophthalmologie
|August 27, 2020
PubMed
Summary

Deep learning models accurately predict visual fields (VF) from OCT scans. Inception-ResNet-v2 demonstrated superior performance, offering a potential alternative for patients unable to complete traditional VF testing.

Keywords:
Deep learningInceptionSwept-source optical coherence tomographyVisual field

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Area of Science:

  • Ophthalmology
  • Medical Imaging
  • Artificial Intelligence

Background:

  • Visual field (VF) testing is crucial for diagnosing and monitoring glaucoma.
  • Wide-angle swept-source optical coherence tomography (SS-OCT) provides detailed retinal imaging.
  • Predicting VF from SS-OCT could offer an alternative for patients unable to perform standard VF tests.

Purpose of the Study:

  • To develop and evaluate deep learning models for predicting visual fields (VF) using SS-OCT data.
  • To compare the performance of three Google Inception architectures (Inception-ResNet-v2, Inception-v3, Inception-v4) for VF prediction.
  • To assess the impact of glaucoma severity and specific retinal sectors on prediction accuracy.

Main Methods:

  • Three deep learning models based on Inception-ResNet-v2, Inception-v3, and Inception-v4 architectures were trained.
  • Models predicted 24-2 VF from macular ganglion cell-inner plexiform layer and peripapillary retinal nerve fibre layer maps from SS-OCT.
  • Prediction performance was quantified using root mean square error (RMSE) and compared across models, glaucoma severities, and Garway-Heath sectors.

Main Results:

  • Inception-ResNet-v2 achieved the lowest global prediction error (RMSE) of 4.44 ± 2.09 dB, significantly outperforming Inception-v3 and Inception-v4 (P < 0.001).
  • Prediction error increased significantly with glaucoma progression, reaching up to 7.79 dB for Inception-v4.
  • The nasal sector showed the lowest prediction error, followed by the superotemporal sector.

Conclusions:

  • The Inception-ResNet-v2 deep learning model demonstrated the best performance in predicting visual fields from SS-OCT data.
  • Prediction accuracy is influenced by glaucoma severity, with higher errors in advanced stages.
  • This AI-driven approach holds promise for clinical applications, especially for patients who cannot undergo conventional visual field testing.