Related Experiment Videos
Postirradiation sarcoma in retinoblastoma. Induction or predisposition?
M B Schwarz1, L P Burgess, W E Fee
1Department of Surgery, Stanford University Medical Center, CA 94305.
Archives of Otolaryngology--Head & Neck Surgery
|June 1, 1988
Summary
High rates of postirradiation sarcomas, predominantly osteogenic sarcoma, occur after retinoblastoma treatment. Genetic factors and radiation likely contribute to sarcoma development years after initial therapy.
Area of Science:
- Oncology
- Genetics
- Radiation Oncology
Background:
- Retinoblastoma treatment, particularly with radiation, is linked to secondary sarcomas.
- Osteogenic sarcoma is the most common histologic type, but fibrosarcoma and others also occur.