Related Experiment Video
Updated: Dec 10, 2025
07:50
A Metadata Extraction Approach for Clinical Case Reports to Enable Advanced Understanding of Biomedical Concepts
Published on: September 20, 2018
16.3K
Chryseobacterium arthrosphaerae ventriculitis: A case report.
Jae Hyoung Im1, Donghwi Kim2, Jin Ju Kim3
1Division of Infectious diseases, Department of Internal Medicine.
Medicine
|August 28, 2020
Summary
Trimethoprim/sulfamethoxazole effectively treated ventriculitis caused by multidrug-resistant Chryseobacterium arthrosphaerae. This antibiotic regimen offers a promising alternative for managing challenging bacterial infections.
Area of Science:
- Infectious Diseases
- Bacteriology
- Clinical Microbiology
Background:
- Chryseobacterium arthrosphaerae is a gram-negative bacterium recognized for inherent multidrug resistance, complicating treatment strategies.
- Nosocomial infections pose significant challenges in clinical settings, particularly in immunocompromised patients or those with indwelling devices.
Observation:
- A 56-year-old male with a 6-month external ventricular drainage catheter presented with cerebrospinal fluid pleocytosis and fever.
- The patient was diagnosed with ventriculitis attributed to Chryseobacterium arthrosphaerae following recurrent nosocomial infections.
Findings:
- Initial treatment with ciprofloxacin, minocycline, and rifampin showed limited efficacy.
- Switching to trimethoprim/sulfamethoxazole in combination with ciprofloxacin led to rapid improvement in pleocytosis and resolution of infection.
Implications:
- Trimethoprim/sulfamethoxazole, alone or with ciprofloxacin, is a potential therapeutic option for Chryseobacterium arthrosphaerae ventriculitis.
- This case highlights the importance of reassessing antibiotic regimens for multidrug-resistant bacterial infections.
Related Concept Videos
01:28Acute Pyelonephritis II: Diagnostic Studies and Management
185
Introduction:For diagnosing acute pyelonephritis, a comprehensive patient history is collected to identify symptoms such as dysuria, frequent or urgent urination, flank pain, or costovertebral angle (CVA) tenderness that may suggest a kidney infection.Physical ExaminationDuring the physical examination, CVA tenderness is assessed. This involves gentle percussion over the costovertebral angle, where tenderness often indicates a kidney infection.Diagnostic TestsUrinalysis: Used to identify white...
185
01:27Acute Pyelonephritis I: Introduction
309
Pyelonephritis is a bacterial infection that primarily affects the renal parenchyma and collecting system, including the renal pelvis, tubules, and interstitial tissue of one or both kidneys. It can be classified as either acute—a sudden, severe infection—or chronic, which refers to long-term or recurrent kidney infections.The primary cause of acute pyelonephritis (APN) is bacterial infection, with Escherichia coli accounting for approximately 70-80% of cases. Other bacteria, such...
309
01:30Acute Pharyngitis
3.0K
Introduction
Acute pharyngitis is the inflammation of the back of the throat (pharynx), commonly resulting in a sore throat. It is a frequently encountered condition that prompts individuals to seek medical advice.
Classification
Acute pharyngitis can be categorized based on its underlying cause:
Acute pharyngitis is the inflammation of the back of the throat (pharynx), commonly resulting in a sore throat. It is a frequently encountered condition that prompts individuals to seek medical advice.
Classification
Acute pharyngitis can be categorized based on its underlying cause:
3.0K
01:25Endocarditis I: Introduction
267
Introduction:Endocarditis is the infection of the endocardium, the inner lining of the heart and its valves. When the heart muscle is involved, the condition is termed myocarditis, while an infection of the outer lining is called pericarditis. Infective endocarditis (IE) primarily affects the endocardium, where pathogens adhere to the valves or lining, forming vegetation that can lead to severe complications. Infective endocarditis occurs when microorganisms, usually bacteria from other body...
267
01:18Endocarditis III: Medical Management
126
Infective endocarditis management involves a multifaceted approach encompassing infection prevention, lifestyle modifications, pharmacological therapy, and surgical management.Infection Prevention:Hand Hygiene: Thorough handwashing is crucial to prevent the spread of infection. Hand hygiene should be performed regularly, especially before and after using the restroom.Oral Hygiene: Good oral hygiene is essential. It includes brushing teeth immediately after waking up and before bed, flossing...
126
01:29Bacterial Phylum Chlamydiae
314
The phylum Chlamydiae or Chlamydiota is composed of a single order, Chlamydiales. This phylum consists entirely of obligate intracellular parasites that infect eukaryotic hosts. While human pathogens within this group have been studied extensively, the phylum encompasses many species capable of interacting with various eukaryotic organisms. Members of Chlamydiae are typically small cocci, approximately 0.5 μm in diameter, and exhibit a distinctive developmental cycle. As is characteristic...
314