Related Experiment Video
Updated: Dec 10, 2025

Large-Scale SARS-CoV-2 Testing Utilizing Saliva and Transposition Sample Pooling
Published on: June 23, 2022
Population-scale longitudinal mapping of COVID-19 symptoms, behaviour and testing
William E Allen1,2,3, Han Altae-Tran4,5,6, James Briggs4,5,7
1The How We Feel Project, San Leandro, CA, USA. weallen@fas.harvard.edu.
None:
Despite the widespread implementation of public health measures, coronavirus disease 2019 (COVID-19) continues to spread in the United States. To facilitate an agile response to the pandemic, we developed How We Feel, a web and mobile application that collects longitudinal self-reported survey responses on health, behaviour and demographics. Here, we report results from over 500,000 users in the United States from 2 April 2020 to 12 May 2020. We show that self-reported surveys can be used to build predictive models to identify likely COVID-19-positive individuals. We find evidence among our users for asymptomatic or presymptomatic presentation; show a variety of exposure, occupational and demographic risk factors for COVID-19 beyond symptoms; reveal factors for which users have been SARS-CoV-2 PCR tested; and highlight the temporal dynamics of symptoms and self-isolation behaviour. These results highlight the utility of collecting a diverse set of symptomatic, demographic, exposure and behavioural self-reported data to fight the COVID-19 pandemic.
Related Concept Videos
Longitudinal Research
Steps in Outbreak Investigation
Principles of Disease Surveillance
Longitudinal Studies
Pie Chart
In a pie chart, the central angle, the arc length of each slice, and the area are directly proportional to the quantity or percentage it represents. Some real-world examples that can be depicted using pie charts include marks obtained by students...
Residuals and Least-Squares Property
If the observed data point lies above the line, the residual is positive, and the line underestimates the actual data value for y. If the observed data point lies below the line, the residual is negative, and the line overestimates the actual data value for y.
The process of fitting the best-fit...

