Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Computed Tomography01:10

Computed Tomography

7.7K
Tomography refers to imaging by sections. Computed tomography (CT) is a non-invasive imaging technique that uses computers to analyze several cross-sectional X-rays to reveal minute details about structures in the body.
The technique was invented in the 1970s and is based on the principle that as X-rays pass through the body, they are absorbed or reflected at different levels. In the technique, a patient lies on a motorized platform while a computerized axial tomography (CAT) scanner rotates...
7.7K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Mid-term complication rate after limb salvage for pediatric bone sarcomas.

Journal of pediatric orthopedics. Part B·2026
Same author

Rate and Type of Surgery and Prevalence of Malignancy in Patients With Ollier's Disease and Maffucci Syndrome.

American journal of medical genetics. Part A·2026
Same author

Tranexamic Acid in Lower Extremity Endoprosthetic Reconstruction for Oncologic Indications: A Retrospective Comparative Study of 617 Patients.

Journal of surgical oncology·2026
Same author

Low Survival Rates for Pediatric Patients with Tumor Thrombus in Sarcoma.

Journal of clinical medicine·2026
Same author

Delays in Pediatric Supracondylar Humerus Fracture Management: A Comparison of Pre- and Postpandemic Trends.

The Journal of the American Academy of Orthopaedic Surgeons·2026
Same author

You Do Not Need to Pull Out the Onion to See if It Is Growing: Treatment of DDH With Closed Reduction and 3 Consecutive Months of Spica Casting.

Journal of pediatric orthopedics·2025
Same journal

Oral Etoposide for Relapsed or Refractory Ewing Sarcoma in Adolescent and Adult Patients.

Sarcoma·2024
Same journal

Incidence of Undifferentiated Pleomorphic Sarcoma (UPS) in the United States.

Sarcoma·2024
Same journal

Desmoplastic Small Round Cell Tumors: Clinical Presentation, Molecular Characterization, and Therapeutic Approach of Seven Patients.

Sarcoma·2024
Same journal

ATRX and Its Prognostic Significance in Soft Tissue Sarcoma.

Sarcoma·2024
Same journal

Factors Influencing the Outcome of Patients with Primary Ewing Sarcoma of the Sacrum.

Sarcoma·2024
Same journal

Exploring the Diagnostic Dilemma of Indeterminate Pulmonary Nodules in Patients with Primary Sarcoma of Bone.

Sarcoma·2024
See all related articles

Related Experiment Video

Updated: Dec 10, 2025

Machine Learning Algorithms for Early Detection of Bone Metastases in an Experimental Rat Model
07:15

Machine Learning Algorithms for Early Detection of Bone Metastases in an Experimental Rat Model

Published on: August 16, 2020

7.2K

Predicting Pathologic Bone Lesions Using Scout Computed Tomography (CT) Imaging.

Michael J Colello1, Erin R Pichiotino1, Stephanie L Tanner1

  • 1Department of Orthopedic Surgery, Prisma Health-Upstate, Greenville, SC 29605, USA.

Sarcoma
|August 28, 2020
PubMed
Summary
This summary is machine-generated.

Reviewing scout CT images aids early detection of bone lesions missed in initial reports. This can expedite treatment for patients with metastatic disease, reducing complications.

More Related Videos

Modeling Primary Bone Tumors and Bone Metastasis with Solid Tumor Graft Implantation into Bone
06:53

Modeling Primary Bone Tumors and Bone Metastasis with Solid Tumor Graft Implantation into Bone

Published on: September 9, 2020

3.1K
Longitudinal Micro-Computed Tomography Image Analysis for User-Defined Region of Interest in Critical-Sized Bone Defects
08:39

Longitudinal Micro-Computed Tomography Image Analysis for User-Defined Region of Interest in Critical-Sized Bone Defects

Published on: June 24, 2025

438

Related Experiment Videos

Last Updated: Dec 10, 2025

Machine Learning Algorithms for Early Detection of Bone Metastases in an Experimental Rat Model
07:15

Machine Learning Algorithms for Early Detection of Bone Metastases in an Experimental Rat Model

Published on: August 16, 2020

7.2K
Modeling Primary Bone Tumors and Bone Metastasis with Solid Tumor Graft Implantation into Bone
06:53

Modeling Primary Bone Tumors and Bone Metastasis with Solid Tumor Graft Implantation into Bone

Published on: September 9, 2020

3.1K
Longitudinal Micro-Computed Tomography Image Analysis for User-Defined Region of Interest in Critical-Sized Bone Defects
08:39

Longitudinal Micro-Computed Tomography Image Analysis for User-Defined Region of Interest in Critical-Sized Bone Defects

Published on: June 24, 2025

438

Area of Science:

  • Oncology
  • Radiology
  • Orthopedics

Background:

  • Routine oncologic surveillance often involves CT imaging.
  • Pathologic bony lesions can be subtle and easily missed on initial interpretation.
  • Early identification of bone lesions is crucial for timely treatment and improved patient outcomes.

Purpose of the Study:

  • To evaluate the benefit of reviewing scout CT images for early identification of pathologic bony lesions.
  • To determine the rate at which lesions are missed in initial CT radiologic reports.
  • To assess the impact of delayed diagnosis on patient morbidity.

Main Methods:

  • Retrospective review of 144 patients treated for humerus or femur lesions (2009-2019).
  • Analysis of available scout CT images obtained prior to official diagnosis.
  • Independent review of scout CT images by two reviewers.
  • Comparison of reviewer findings with initial radiologic reports.

Main Results:

  • 39 patients had available scout CT images prior to diagnosis.
  • Authors identified lesions in 64.1% of scout CTs, versus 23.1% documented in initial reports.
  • 65.5% of identified lesions were not reported initially, with an average delay of 202 days to diagnosis.
  • 16.7% of impending fractures progressed to complete fracture before orthopedic referral, with an average delay of 68 days.

Conclusions:

  • Careful review of scout CT imaging is essential for detecting pathologic bony lesions.
  • Utilizing scout CTs as a screening tool can expedite diagnosis and treatment.
  • Early detection and treatment of metastatic bone disease can reduce patient morbidity.