Effect of Process-Based Multi-Task Cognitive Training Program on Executive Function in Older Adults With Mild...

Area of Science:

• Neuroscience
• Gerontology
• Cognitive Psychology

Background:

• Cognitive training shows benefits for older adults with mild cognitive impairment (MCI).
• Executive function training's long-term effectiveness and transfer effects in MCI are understudied.
• This research addresses the gap in understanding executive function training for MCI.

Purpose of the Study:

• Evaluate process-based multi-task cognitive training's effect on executive function in older adults with MCI.
• Explore the long-term and transfer effects of this cognitive training intervention.
• Investigate the neural correlates of cognitive performance changes post-intervention.

Main Methods:

• Single-blinded, randomized, prospective clinical trial.
• Ninety participants with MCI assigned to cognitive training (n=45) or wait-list control (n=45).
• 10-week intervention with assessments at baseline, post-intervention, and 3-month follow-up using neuropsychological tests and EEG.

Main Results:

• The study is ongoing; recruitment concluded in 2020.
• Analysis will include intention-to-treat and protocol set principles.
• Potential long-term and transfer effects will be explored.

Conclusions:

• Positive changes in executive function could offer a viable strategy to delay cognitive decline in MCI.
• The findings may support process-based multi-task cognitive training as a therapeutic approach.
• Further research will elucidate the neural mechanisms underlying cognitive improvements.