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Published on: July 18, 2014
Giant Right Atrial Abscess in a Premature Infant With Fungal Endocarditis in a Developing Country
Nicola Pradegan1,2, Ysailis Mariñez Muñoz2, Marcos Reyes3
1Cardiac Surgery Unit, Department of Cardiac, Thoracic, Vascular Sciences and Public Health, 9308Padua University Hospital, Padua, Italy.
Abstract:
Although infective endocarditis rarely appears during infancy, fungal infections remain a concern in the preterm neonatal population as the result of compromised immunity, prolonged hospitalization, and invasive procedures. The increased awareness of fungal colonization and improvements in medical therapy have not reduced the high mortality rate of mycotic infections in premature newborns, especially in developing countries, and there is no consensus on the surgical timing to treat neonatal fungal endocarditis. We present the case of a two-month-old boy with a history of three weeks of hospitalization for prematurity. After being discharged, the patient developed symptomatic candidemia resulting from a large right atrial abscess obstructing the tricuspid valve; despite antifungal therapy, urgent surgical resection was required.
Insights
Neonatal fungal endocarditis, a serious concern in premature infants, requires urgent surgical intervention for abscesses obstructing heart valves, even with antifungal treatment. This case highlights the critical need for timely surgical management in high-risk neonates.
Area of Science:
- Neonatology
- Infectious Diseases
- Cardiology
Background:
- Fungal infections, such as infective endocarditis, pose a significant mortality risk in preterm neonates due to immature immunity and invasive medical procedures.
- Despite advancements, high mortality rates persist in premature newborns with mycotic infections, particularly in developing nations.
- Current guidelines lack consensus on optimal surgical timing for neonatal fungal endocarditis.
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Endocarditis III: Medical Management
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Endocarditis IV: Nursing Management

