[Genetic aspects of systematic mineralization disorders]
1Institut für Tierzucht der Tierärztlichen Hochschule Hannover.
Summary
Intensive animal selection for rapid growth and meatiness causes health issues like leg weakness and osteochondrosis. These correlated effects highlight the need to balance economic traits with animal welfare and biological limits.
Area of Science:
- Animal Genetics and Breeding
- Veterinary Pathology
- Animal Physiology
Context:
- Intensive selection for high daily gains and meatiness in livestock has led to unintended biological maladaptations.
- These issues include myopathies, stress predisposition, leg weakness in pigs, and dyschondroplasias in broilers, affecting bones, cartilage, and joints.
Purpose:
- To investigate the genetic and environmental factors contributing to maladaptations like osteochondrosis.
- To analyze the variability in mineral utilization and bone/cartilage health across different breeds and individuals.
- To assess the feasibility of selective measures to counteract negative correlated effects.
Summary:
- Forced selection for growth and meatiness induces genetic-hormonal maladaptations, including skeletal disorders such as osteochondrosis.
- Variability in these conditions, even within pure breeds under identical conditions, suggests a complex interplay of heredity and environment.
- Mineral utilization and biomechanical bone strength show significant individual differences, with heritability estimates for skeletal issues exceeding those for leg weakness.
Impact:
- Findings suggest that rigorous selection for a few traits may exceed biological limits in some domestic animal populations.
- Highlights the need for balanced breeding strategies that consider animal welfare and prevent skeletal pathologies.
- Provides evidence for the potential of selective measures to mitigate negative correlated effects in animal breeding programs.
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