Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Renal involvement in AIDS: sonographic-pathologic correlation.

U M Hamper1, L E Goldblum, G M Hutchins

  • 1Department of Radiology and Radiological Science, Johns Hopkins Medical Institutions, Baltimore, MD 21205.

AJR. American Journal of Roentgenology
|June 1, 1988
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Hemodynamic measurements in human arterial casts, and their correlation with histology and luminal area.

Journal of biomechanical engineering·2009
Same author

A case-control study of the pathology of oesophageal disease in systemic sclerosis (scleroderma).

Gut·2006
Same author

Filamin A mutations cause periventricular heterotopia with Ehlers-Danlos syndrome.

Neurology·2005
Same author

Controversies in female urethral anatomy and their significance for understanding urinary continence: observations and literature review.

International urogynecology journal and pelvic floor dysfunction·2002
Same author

Von Willebrand factor-cleaving protease activity and proteolysis of von Willebrand factor in bone marrow transplant-associated thrombotic microangiopathy.

The hematology journal : the official journal of the European Haematology Association·2002
Same author

Pathogenesis of acardiac twinning: clues from an almost acardiac twin.

Fetal diagnosis and therapy·2002
Same journal

The Banality of Cancer: Entropy As a Third Pillar of Lung Nodule Risk Assessment.

AJR. American journal of roentgenology·2026
Same journal

A Narrow Window for Artificial Intelligence-Generated Synthetic Temporal Bone CT From MRI.

AJR. American journal of roentgenology·2026
Same journal

From Uncertainty to Actionable Management: The Isolated Abnormal Axillary Lymph Node.

AJR. American journal of roentgenology·2026
Same journal

Beyond Detection: Translating Artificial Intelligence-Driven Opportunistic Screening Into Clinical Action.

AJR. American journal of roentgenology·2026
Same journal

Navigating PSMA PET Radiopharmaceuticals: Clinical and Operational Factors.

AJR. American journal of roentgenology·2026
Same journal

From Mesenteric Ischemia to Intestinal Stroke.

AJR. American journal of roentgenology·2026
See all related articles

Renal sonography in patients with acquired immunodeficiency syndrome (AIDS) revealed that striking tubular abnormalities, not just glomerular changes, are the primary cause of increased renal echogenicity in AIDS nephropathy.

Area of Science:

  • Nephrology
  • Radiology
  • Pathology

Background:

  • Acquired immunodeficiency syndrome (AIDS) can lead to deteriorating renal function.
  • Renal abnormalities are common in patients with AIDS.

Purpose of the Study:

  • To correlate sonographic findings of renal echogenicity with histopathologic changes in patients with AIDS.
  • To identify the underlying causes of increased renal echogenicity in AIDS nephropathy.

Main Methods:

  • Renal sonography was performed on 36 patients with AIDS and evidence of renal dysfunction.
  • Histopathologic examination of renal specimens from 15 patients was conducted.
  • Sonographic evaluation included renal size and cortical echogenicity grading.
  • Pathologic evaluation focused on tubular and glomerular abnormalities.

Related Experiment Videos

Main Results:

  • Thirteen patients (36%) showed grade I cortical echogenicity, three (8%) grade II, and five (14%) grade III. Fifteen patients (42%) had normal echogenicity.
  • Histopathology revealed focal segmental glomerulosclerosis and varying degrees of tubular abnormalities.
  • Striking tubular dilatation, infolding, and proteinaceous deposits were observed in patients with grade III echogenicity.
  • Tubular abnormalities correlated with increased renal echogenicity, particularly in grade III cases.

Conclusions:

  • Glomerular changes contribute to increased renal echogenicity in AIDS nephropathy.
  • Striking tubular abnormalities are postulated as the main factor responsible for increased renal echogenicity in AIDS nephropathy.
  • Sonography can detect renal changes associated with AIDS, with echogenicity reflecting underlying pathology.