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Related Experiment Videos

Sonographic findings in infants with macrocrania.

D S Babcock1, B K Han, M S Dine

  • 1Department of Radiology, Children's Hospital Medical Center, Cincinnati, OH 45229-2899.

AJR. American Journal of Roentgenology
|June 1, 1988
PubMed
Summary

Sonography is a reliable initial tool for diagnosing macrocrania in infants, accurately assessing fluid spaces and malformations. It effectively guides further diagnostic imaging, with CT scans rarely providing additional crucial information.

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Area of Science:

  • Pediatric Radiology
  • Neuroimaging in Infants
  • Diagnostic Accuracy Studies

Background:

  • Macrocrania in infants presents a diagnostic challenge, requiring differentiation between benign and pathological causes.
  • Sonography and computed tomography (CT) are imaging modalities used to evaluate infants with enlarged heads.
  • Correlation of imaging findings with neurologic outcomes is essential for understanding prognostic value.

Purpose of the Study:

  • To compare sonographic and CT findings in infants with macrocrania.
  • To correlate imaging findings with neurologic outcomes.
  • To determine the diagnostic accuracy and prognostic value of sonography in pediatric macrocrania.

Main Methods:

  • Retrospective analysis of sonographic findings in 255 infants with macrocrania.

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  • Comparison of sonographic and CT findings in a subset of 36 infants.
  • Neurologic follow-up data collection for 202 patients.

    • Main Results:

    • Sonography identified significant abnormalities in 5.6% of term and 6.7% of preterm infants.
    • Good correlation was observed between sonography and CT in most cases, with CT rarely adding information.
    • Most infants with normal sonograms had normal neurologic outcomes, though some showed developmental delays.

    Conclusions:

    • Sonography is a recommended initial imaging procedure for infants with macrocrania due to its accuracy in evaluating ventricular size, fluid spaces, and malformations.
    • Normal sonographic findings or mildly increased fluid spaces often suffice with clinical follow-up.
    • CT is indicated for significant sonographic abnormalities requiring further clarification.