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A Murine Model of Ischemic Retinal Injury Induced by Transient Bilateral Common Carotid Artery Occlusion
Published on: November 12, 2020
Inflammation of a Posterior Ciliary Artery in a Naive Cynomolgus Macaque
Steven T Laing1, Marie M Bockenstedt2, Helen S Booler1
1Department of Safety Assessment, 7412Genentech Inc, South San Francisco, CA, USA.
Abstract:
This brief communication describes a previously unreported background lesion in the eye of a naive cynomolgus macaque. Inflammation of a posterior ciliary artery was, in this case, morphologically similar to vascular inflammation of other tissues described in naive cynomolgus macaques. However, the available literature does not describe this lesion at this anatomical site. The affected animal did not present with any abnormal clinical signs and ophthalmological examinations were within normal limits. Toxicologic pathologists should be aware of this finding in order to help differentiate it from a test item-related finding.

