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Half-life extension of peptidic APJ agonists by N-terminal lipid conjugation

Anthony B Reed1, Brian A Lanman1, Jerry Ryan Holder2

  • 1Department of Medicinal Chemistry, Amgen Research, One Amgen Center Drive, Thousand Oaks, CA 91320, USA.

Bioorganic & Medicinal Chemistry Letters
|August 29, 2020
PubMed

Keywords:
APJ receptorAbsorptive phaseApelinFree plasma concentrationLipid conjugate

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