Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Inflammatory response to implants.

J M Anderson1

  • 1Department of Pathology, Case Western Reserve University, Cleveland, Ohio 44106.

ASAIO Transactions
|April 1, 1988
PubMed
Summary
This summary is machine-generated.

The body

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Changes in lipoprotein(a) levels measured by six kit methods during growth hormone treatment of growth hormone-deficient adults.

Growth hormone & IGF research : official journal of the Growth Hormone Research Society and the International IGF Research Society·2001
Same author

Shear stress-induced apoptosis of adherent neutrophils: a mechanism for persistence of cardiovascular device infections.

Proceedings of the National Academy of Sciences of the United States of America·2000
Same author

High molecular weight kininogen inhibition of endothelial cell function on biomaterials.

Journal of biomedical materials research·2000
Same author

Monocyte adhesion to platelet concentrate storage bags and cytokine production.

Vox sanguinis·2000
Same author

Early diagnosis of right ventricular or posterior infarction associated with inferior wall left ventricular acute myocardial infarction.

The American journal of cardiology·2000
Same author

CaCo-2 cells treated with Clostridium perfringens enterotoxin form multiple large complex species, one of which contains the tight junction protein occludin.

The Journal of biological chemistry·2000
Same journal

Extracorporeal membrane oxygenation as a means of stabilizing and transporting high risk neonates.

ASAIO transactions·1991
Same journal

Pumping capabilities of the latissimus dorsi and rectus abdominis muscles wrapped around a valved pouch in a mock circulatory system.

ASAIO transactions·1991
Same journal

Causes of intraaortic balloon leaks.

ASAIO transactions·1991
Same journal

Influence of centrifugal blood pumps on the elasticity of erythrocytes.

ASAIO transactions·1991
Same journal

Reuse of "highly permeable" dialyzers with peroxyacetic acid as sole cleansing and disinfecting agent.

ASAIO transactions·1991
Same journal

Comparison of 50% dextrose water, 25% mannitol, and 23.5% saline for the treatment of hemodialysis-associated muscle cramps.

ASAIO transactions·1991
See all related articles

Area of Science:

  • Biomaterials Science
  • Immunology
  • Tissue Engineering

Background:

  • Implantation of artificial organs, medical devices, or biomaterials triggers an inflammatory response.
  • This response includes acute and chronic inflammation, foreign body reactions, and cellular interactions (macrophages, foreign body giant cells).
  • Implant surface characteristics influence the foreign body reaction's composition.

Purpose of the Study:

  • To describe the inflammatory response to implanted biomaterials.
  • To highlight the pivotal role of macrophages in tissue response to implants.
  • To present a hypothesis on complement activation's role in cellular adhesion to implant surfaces.

Main Methods:

  • Review of inflammatory response components to implants.

Related Experiment Videos

  • Analysis of macrophage and foreign body giant cell interactions.
  • Description of complement activation and cell adhesion mechanisms.

    • Main Results:

    • The foreign body reaction involves macrophages and foreign body giant cells at the implant surface.
    • Fibroblastic proliferation, collagen deposition, and capillary formation are observed.
    • Macrophage adhesion and activation are critical for cell-mediated communication.

    Conclusions:

    • Macrophages are central to the tissue response following implantation.
    • Surface topography of implants significantly impacts the foreign body reaction.
    • Complement activation may mediate cellular adhesion to implant surfaces.