Related Experiment Video
Updated: Dec 10, 2025
Environmental Dynamic Mechanical Analysis to Predict the Softening Behavior of Neural Implants
Published on: March 1, 2019
Stability Performance Analysis of Various Packaging Materials and Coating Strategies for Chronic Neural Implants
Yan Gong1, Wentai Liu1, Runyu Wang1
1Department of Electrical and Computer Engineering, Michigan State University, East Lasing, MI 48824, USA.
Abstract:
Reliable packaging for implantable neural prosthetic devices in body fluids is a long-standing challenge for devices' chronic applications. This work studied the stability of Parylene C (PA), SiO2, and Si3N4 packages and coating strategies on tungsten wires using accelerated, reactive aging tests in three solutions: pH 7.4 phosphate-buffered saline (PBS), PBS + 30 mM H2O2, and PBS + 150 mM H2O2. Different combinations of coating thicknesses and deposition methods were studied at various testing temperatures. Analysis of the preliminary data shows that the pinholes/defects, cracks, and interface delamination are the main attributes of metal erosion and degradation in reactive aging solutions. Failure at the interface of package and metal is the dominating factor in the wire samples with open tips.
