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No intrauterine vertical transmission in pregnancy with COVID-19: A case report

Yantian Lv1, Binbin Gu2, Ying Chen1

  • 1Department of Respiratory and Critical Medicine, Affiliated Suzhou Hospital of Nanjing Medical University, Suzhou, China.

Journal of Infection and Chemotherapy : Official Journal of the Japan Society of Chemotherapy
|August 30, 2020
PubMed

Insights

Critical COVID-19 in pregnancy is concerning. This case study found no severe acute respiratory syndrome coronavirus 2 (SARS-COV-2) in a neonate or maternal samples, suggesting no vertical transmission in the third trimester.

Area of Science:

  • Obstetrics and Gynecology
  • Infectious Diseases
  • Neonatology

Background:

  • The COVID-19 pandemic has raised concerns about pregnant women and neonates.
  • Limited data exists on the impact of SARS-COV-2 infection on pregnancy outcomes and neonatal health.

Observation:

  • A case of a pregnant woman in her third trimester with critical COVID-19 is presented.
  • Samples including amniotic fluid, umbilical cord blood, placenta, and neonatal gastric fluid were collected during cesarean delivery.

Findings:

  • All tested specimens (amniotic fluid, cord blood, placenta, neonatal gastric fluid) were negative for SARS-COV-2 nucleic acid.
  • No evidence of intrauterine vertical transmission of SARS-COV-2 was detected in this third-trimester pregnancy.

Implications:

  • This case suggests a potential lack of vertical transmission in late-term pregnancies, but further research is crucial.
  • Findings contribute to understanding the risks of COVID-19 in pregnancy and potential neonatal outcomes.

Keywords:
COVID-19Intrauterine vertical transmissionPregnancyPrognosisSARS-COV-2

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