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Outcomes after appendectomy in children with acute appendicitis treated at a tertiary paediatric centre: results from
Max Knaapen1, Paul van Amstel2, Tim van Amstel2
1Department of Paediatric Surgery, Emma Children's Hospital, Amsterdam UMC, University of Amsterdam & Vrije Universiteit Amsterdam, PO Box 22660, 1100DD, Amsterdam, The Netherlands. M.Knaapen@amsterdamumc.nl.
Insights
Appendectomy in children has a higher complication rate than previously thought, especially in complex cases. These findings highlight the need for ongoing optimization of appendicitis treatment strategies.
Area of Science:
- Pediatric Surgery
- Surgical Outcomes
- Appendicitis Management
Background:
- Appendectomy is generally considered a low-risk procedure.
- Reported complication rates following appendectomy in children vary significantly in existing literature.
Purpose of the Study:
- To investigate the incidence of post-appendectomy complications in pediatric patients diagnosed with acute appendicitis.
- To provide updated data on complication rates to inform clinical practice and future research.
Main Methods:
- A retrospective cohort study was conducted on 131 children (0-17 years) who underwent appendectomy for acute appendicitis between January 2011 and December 2018.
- Complications were identified from electronic medical records and classified using the Clavien-Dindo grading system (I-II for less severe, III-IV for severe).
- Exclusion criteria included referred cases and non-operative management.
Main Results:
- Overall, 33% of patients experienced one or more complications.
- Children with simple appendicitis had a 12% complication rate (3 severe), while those with complex appendicitis had a 38% complication rate (14 severe).
- The study observed a higher complication incidence than reported in much of the current literature.
Conclusions:
- The findings indicate a substantial rate of complications following pediatric appendectomy, particularly in cases of complex appendicitis.
- The higher rates may be attributed to the study's definitions and the center's status as a tertiary referral facility managing more severe cases.
- Appendectomy should not be viewed as a routine procedure with minimal risk, emphasizing the need for continued improvement in appendicitis treatment.
Purpose:
In general, an appendectomy is presumed to have a limited burden of disease. However, in current literature, reported complication rates vary. This study aims to provide additional insights in the incidence of post-appendectomy complications in children with acute appendicitis.
Methods:
This retrospective cohort study included children (0-17 years old) that underwent appendectomy at our tertiary referral centre for suspected acute appendicitis (January 2011-December 2018). Children referred to our centre, and those that underwent non-operative treatment were excluded. Post-appendectomy complications were recorded from electronic medical charts using predefined definitions and classified as severe (Clavien-Dindo III-IV) or less severe (Clavien-Dindo I-II).
Results:
A total of 131 children were included. Simple and complex appendicitis was diagnosed in 66 (50%) and 60 (46%) children, respectively. A non-inflamed appendix was seen in five (4%) children. One or more complications were identified in 33 (25%) patients. Eight (12%) children with simple appendicitis developed a complication, three of these were severe. In children with complex appendicitis, 23 (38%) children developed a complication, 14 of these were severe.
Conclusion:
This study shows a high rate of complications compared with current literature, both in children with simple and complex appendicitis. This is probably the result of our definition of complications and being a tertiary referral centre receiving more severe appendicitis cases. However, these results still show that appendectomy is not always a routine procedure with only few complications. Substantiating the need to keep optimizing treatment for children with appendicitis.
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