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Related Experiment Video

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Biliary Dyskinesia: Fact or fiction?

M Coluccio1, A J Claffey1, D H Rothstein2

  • 1University at Buffalo Jacobs School of Medicine and Biomedical Sciences, 818 Ellicott St, Buffalo, New York, 14203, USA.

Seminars in Pediatric Surgery
|August 31, 2020
PubMed
Summary

Biliary dyskinesia is a common reason for pediatric gallbladder removal, but surgery doesn't always help. This review covers diagnosis and treatment for abnormal gallbladder emptying in children.

Keywords:
Biliary dyskinesiaBiliary hyperkinesiaCholecystectomyGallbladder emptying

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Area of Science:

  • Pediatric surgery
  • Gastroenterology
  • Nuclear medicine

Background:

  • Cholecystectomy is increasingly performed in pediatric patients.
  • Biliary dyskinesia is now the primary indication for pediatric cholecystectomy in the USA, surpassing gallstones.
  • Not all pediatric patients with abnormal gallbladder emptying benefit from cholecystectomy.

Purpose of the Study:

  • To review current data on the presentation, diagnosis, and treatment of pediatric patients with abnormal gallbladder emptying.
  • To provide insights into the management of biliary dyskinesia in children.

Main Methods:

  • Literature review of studies on pediatric gallbladder emptying disorders.
  • Analysis of data regarding presentation, diagnostic workup, and treatment outcomes.
  • Focus on nuclear medicine scan findings for gallbladder ejection fraction.

Main Results:

  • Biliary dyskinesia is the leading indication for cholecystectomy in US pediatric patients.
  • Abnormal gallbladder emptying rates (low or high) do not guarantee surgical success.
  • Variability exists in patient response to cholecystectomy for this condition.

Conclusions:

  • Further research is needed to optimize the management of pediatric biliary dyskinesia.
  • Careful patient selection and understanding of treatment outcomes are crucial.
  • This review synthesizes current knowledge to guide clinical practice.