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Ivermectin: Potential Role as Repurposed Drug for COVID-19

Alok Dixit1, Ramakant Yadav2, Amit Vikram Singh1

  • 1Department of Pharmacology, Uttar Pradesh University of Medical Sciences, Uttar Pradesh, India.

The Malaysian Journal of Medical Sciences : MJMS
|September 1, 2020
PubMed

Insights

This study explores repurposed drugs for COVID-19, focusing on ivermectin (IVM) as a potential therapeutic option. It highlights the need for rapid response measures during the pandemic.

Area of Science:

  • Virology
  • Infectious Diseases
  • Pharmacology

Background:

  • Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) causes COVID-19, a highly communicable disease declared a pandemic by the WHO.
  • Limited understanding of SARS-CoV-2 pathogenesis and proliferation necessitates rapid therapeutic strategies.
  • Development of novel vaccines and drugs is ongoing but requires significant time for safety and efficacy testing.

Purpose of the Study:

  • To review currently used repurposed drugs for COVID-19 treatment.
  • To evaluate the potential of ivermectin (IVM) as a therapeutic option for COVID-19.
  • To discuss rapid response measures for the ongoing pandemic.

Main Methods:

  • Literature review of existing repurposed drugs for COVID-19.
  • Analysis of scientific data regarding the potential efficacy and safety of ivermectin (IVM).
  • Discussion of ivermectin's role as a repurposed therapeutic agent.

Main Results:

  • Several existing drugs are being repurposed for COVID-19 treatment.
  • Ivermectin (IVM) shows potential as a therapeutic option, warranting further investigation.
  • Repurposing drugs with established safety profiles offers a rapid response to the pandemic.

Conclusions:

  • Repurposing existing drugs is a crucial strategy for managing the COVID-19 pandemic.
  • Ivermectin (IVM) presents a promising therapeutic avenue for COVID-19.
  • Continued research into repurposed agents is essential for effective pandemic response.

Keywords:
SARS-CoV-2antiparasiticcoronavirus disease 2019drug repurposingivermectin

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