Emerging evidence of myocardial injury in COVID-19: A path through the smoke
Gregorio Tersalvi1,2, Giacomo Veronese3,4, Dario Winterton3,4
1Division of Cardiology, Fondazione Cardiocentro Ticino, Lugano, Switzerland.
Insights
Cardiac troponin I levels can predict mortality in patients with Coronavirus Disease 2019 (COVID-19). Even small increases in this biomarker indicate a higher risk of death, aiding early risk assessment for COVID-19 patients.
Area of Science:
- Cardiology
- Infectious Diseases
- Biomarkers
Background:
- Coronavirus Disease 2019 (COVID-19) is increasingly recognized as a systemic illness beyond respiratory symptoms.
- Myocardial damage is a documented complication of COVID-19, with ongoing research into its underlying mechanisms.
Abstract:
Although Coronavirus Disease 2019 (COVID-19) presents primarily as a respiratory condition, a growing body of evidence shows it is a systemic disease. Recently, many authors have described myocardial damage in COVID-19, suggesting various pathophysiological mechanisms. In this issue, Cao et al. demonstrate the prognostic value of cardiac troponin I in patients with COVID-19, showing how even minor elevations in this molecule carry a great impact on patient mortality. In a situation such as the worldwide COVID-19 pandemic, where healthcare resources are placed under enormous stress, readily available tests such as this play an important role in helping clinicians identify patients at greater risk of developing severe forms of the disease, and should be included in the initial triage panel.
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