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Stem Cell Culture01:17

Stem Cell Culture

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Stem cell research aims to find ways to use stem cells to regenerate and repair cellular damage. Over time, most adult cells undergo the wear and tear of aging and lose their ability to divide and repair themselves. Stem cells do not display a particular morphology or function. Adult stem cells, which exist as a small subset of cells in most tissues, keep dividing and can differentiate into a number of specialized cells generally formed by that tissue. These cells enable the body to renew and...
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Stem Cell Niche01:26

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The stem cell niche is the dynamic microenvironment where stem cells reside. Inside these niches, the cells may remain undifferentiated, undergo high self-renewal, or become lineage-specific progenitors. Stem cells coexist with other niche cells, such as stromal cells. They also interact closely with the ECM. Cell-cell and cell-matrix communication occur via adhesion molecules or soluble factors that signal the stem cells and determine their fate. Stromal cells also provide survival signals to...
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Stem Cell Therapy for Tissue Regeneration01:21

Stem Cell Therapy for Tissue Regeneration

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Stem cell therapy is a method used in regenerative medicine to repair and restore function to damaged tissues and organs. Stem cells have the potential to proliferate and differentiate into various tissue types, making them ideal candidates for tissue regeneration. For example, hematopoietic stem cell transplants are commonly used in blood cancer treatment to replenish damaged bone marrow and restore healthy blood cells.
Types of Stem Cells used in Stem Cell Therapy
The two main cell...
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Source And Potency Of Stem Cells01:27

Source And Potency Of Stem Cells

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Stem cells are undifferentiated cells with extensive self-renewal properties that help them maintain their population during the fetal and adult stages of life. They can specialize in all cell types of the human body. However, their differential potential may vary and can be classified into five types. Stem cells can be (1) Totipotent, (2) Pluripotent, (3) Multipotent, (4) Oligopotent, and (5) Unipotent. Each stem cell has a specific origin; the fertilized egg or zygote is a totipotent cell and...
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Sustainable Development01:43

Sustainable Development

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As the human population continues to grow and use resources, we must be mindful of our planet’s natural limits. Sustainable development provides a pathway to maintain and improve human life now while also ensuring that future generations will have the resources that they need. The long-term success of sustainability efforts rests on understanding the interplay between human actions and ecological systems.
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Bioremediation00:46

Bioremediation

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Bioremediation is the use of prokaryotes, fungi, or plants to remove pollutants from the environment. This process has been used to remove harmful toxins in groundwater as a byproduct of agricultural run-off and also to clean up oil spills.
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Related Experiment Video

Updated: Dec 10, 2025

The use of SC1 Pluripotin to Support mESC Self-renewal in the Absence of LIF
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The Life Sciences Learning Center: An Evolving Model for a Sustainable STEM Outreach Program.

Danielle C Alcéna-Stiner1,2, Dina G Markowitz2

  • 1School of Nursing, University of Rochester Medical Center, Rochester, New York.

Journal of STEM Outreach
|September 1, 2020
PubMed
Summary
This summary is machine-generated.

The Life Sciences Learning Center (LSLC) offers hands-on STEM education for secondary students, boosting science literacy and enthusiasm. Its sustainable model, supported by NIH grants, disseminates curriculum nationwide.

Keywords:
Curriculum DevelopmentHealth LiteracyInformal Science EducationSTEM OutreachScience OutreachSecondary Science EducationSummer Science ProgramTeacher Professional Development

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Area of Science:

  • Life Sciences Education
  • STEM Outreach

Background:

  • The Life Sciences Learning Center (LSLC) at the University of Rochester's School of Medicine and Dentistry provides hands-on science education.
  • It targets secondary students (grades 6-12) with case-based learning to enhance science literacy and enthusiasm.

Purpose of the Study:

  • To describe the LSLC's model for science education and its sustainability.
  • To highlight its role in curriculum development, dissemination, and adaptation to evolving educational needs.

Main Methods:

  • The LSLC utilizes hands-on, case-based, and inquiry-based learning approaches.
  • Curriculum materials are developed and disseminated through on-site programs, in-school sessions, online resources, and teacher professional development.
  • Partnerships, including one with Science Take-Out, aid in curriculum dissemination and evaluation.

Main Results:

  • The LSLC has operated sustainably for over 20 years, supported by diverse funding, including multiple NIH Science Education Partnership Awards (SEPA).
  • Its curriculum materials have been disseminated nationwide, reaching numerous students and educators.
  • The center has successfully adapted its programs to meet the evolving demands for real-world STEM learning.

Conclusions:

  • The LSLC serves as a successful model for sustainable science outreach and curriculum development.
  • Its approach effectively increases science literacy and enthusiasm among secondary students.
  • The center's adaptability ensures its continued relevance in STEM education.