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Systemic Lupus Erythematosus and Critical Illness
Erin K Gasser1, Hildy M Schell-Chaple2
1Erin K. Gasser is Critical Care Nurse Practitioner at University of California, San Francisco Health, San Francisco, California.
AACN Advanced Critical Care
|September 1, 2020
Summary
Systemic lupus erythematosus (SLE) is a chronic autoimmune disease causing organ damage and requiring critical care. Management involves understanding its epidemiology, clinical features, diagnosis, and treatments for better patient outcomes.
Area of Science:
- Rheumatology
- Critical Care Medicine
- Immunology
Background:
- Systemic lupus erythematosus (SLE) is a complex autoimmune disorder.
- SLE can lead to diverse, severe conditions necessitating hospitalization and intensive care.
- Patient outcomes are influenced by disease activity-related organ damage and immunosuppressive therapy side effects.
Observation:
- Morbidity and mortality in SLE are linked to cumulative organ damage.
- Chronic or intermittent disease flares contribute significantly to patient morbidity.
- Long-term immunosuppressant regimens present substantial complications.
Findings:
- This review synthesizes essential information for critical care clinicians managing SLE patients.
- Key areas covered include epidemiology, clinical presentation, and diagnostic approaches.
- Therapeutic strategies relevant to critical care settings are discussed.
Implications:
- Enhanced understanding of SLE is crucial for critical care providers.
- Improved diagnostic and therapeutic approaches can mitigate SLE complications.
- This review aims to optimize the critical care of patients with systemic lupus erythematosus.
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