Hepatitis C Virus

Area of Science:

• Hepatology
• Infectious Diseases
• Public Health

Background:

• Hepatitis C virus (HCV) is a prevalent bloodborne pathogen in the United States, with approximately 2.4 million individuals chronically infected.
• A significant portion of those infected remain unaware of their condition, highlighting a critical gap in diagnosis and care.
• Despite the high prevalence, highly effective and well-tolerated therapies with simplified treatment protocols are now available.

Purpose of the Study:

• To emphasize the national goal of eradicating Hepatitis C virus (HCV).
• To highlight the necessity of expanding treatment access to hard-to-reach populations, including persons who inject drugs.
• To underscore the crucial role of primary care providers in managing HCV, from screening to treatment.

Main Methods:

• Review of current HCV treatment landscape and epidemiological data.
• Analysis of treatment access barriers for key populations.
• Assessment of the potential impact of primary care integration in HCV management.

Main Results:

• Highly effective and well-tolerated therapies for HCV are readily available.
• Simplified treatment algorithms are now in place, facilitating broader application.
• Eradication of HCV is a stated national objective.

Conclusions:

• Achieving HCV eradication necessitates increased access to treatment for all populations, particularly persons who inject drugs.
• Primary care providers are essential for screening, stratifying patients, and administering treatment to combat the HCV burden.
• Addressing the significant disease burden requires a comprehensive strategy involving expanded screening and treatment initiatives.