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Perceval Sutureless Aortic Valve Implantation: Midterm Outcomes.
Delphine Szecel1, Roxanne Eurlings1, Filip Rega1
1Department of Cardiovascular Diseases, University Hospitals Leuven, Leuven, Belgium.
The Annals of Thoracic Surgery
|September 1, 2020
Summary
The Perceval sutureless valve shows excellent long-term results in aortic valve replacement, with low mortality and stroke rates over 11 years. This rapid-deployment valve offers significant benefits for patients undergoing surgical aortic valve replacement.
Area of Science:
- Cardiovascular Surgery
- Biomaterials Science
- Medical Devices
Background:
- The Perceval sutureless valve was evaluated in a first-in-human trial in 2007.
- This study provides the longest clinical follow-up (11 years) for sutureless aortic valve replacement technology.
Purpose of the Study:
- To assess the long-term clinical outcomes and hemodynamic performance of the Perceval sutureless valve.
- To evaluate the safety and efficacy of sutureless aortic valve replacement in a large patient cohort.
Main Methods:
- A retrospective analysis of 468 consecutive patients who received the Perceval valve between 2007 and 2017.
- Collection of clinical and echocardiographic data, including mortality, stroke rates, and valve function.
Main Results:
- Low 30-day mortality (3.2%) and stroke rate (1.8%).
- Excellent long-term survival with 1-year (8.8%) and 2-year (13.2%) all-cause mortality.
- Good hemodynamic profile with stable gradients over time; no structural valve degeneration requiring reoperation.
Conclusions:
- The Perceval sutureless valve demonstrates favorable long-term outcomes with low complication rates.
- The valve's rapid deployment and good hemodynamic performance offer added value in surgical aortic valve replacement.
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