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Multimodality imaging in connective tissue disease-related interstitial lung disease.

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  • 1Radiology Department, Hospital de Santa Marta, Centro Hospitalar Universitário de Lisboa Central, Lisboa, Portugal; Radiology Department, Hospital da Luz, Lisboa, Portugal; NOVA Medical School, Universidade Nova de Lisboa, Lisboa, Portugal.

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Interstitial lung disease (ILD) in connective tissue disease (CTD) requires early detection. This review details imaging findings for diagnosing and characterizing CTD-related ILD.

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Area of Science:

  • Rheumatology
  • Pulmonology
  • Radiology

Background:

  • Interstitial lung disease (ILD) is a significant complication of connective tissue diseases (CTDs), impacting patient morbidity and mortality.
  • ILD can present alongside established CTD or as an early sign of an undiagnosed autoimmune disorder.
  • Accurate diagnosis and characterization of CTD-related ILD are crucial for effective patient management.

Purpose of the Study:

  • To review the imaging features of interstitial lung disease in patients with connective tissue diseases.
  • To elucidate the role of various imaging modalities in the diagnosis and characterization of CTD-related ILD.

Main Methods:

  • Review of current literature on imaging techniques for CTD-related ILD.
  • Discussion of findings from computed tomography (CT), ultrasound (US), magnetic resonance imaging (MRI), and positron-emission tomography (PET).

Main Results:

  • Computed tomography is the primary imaging modality for CTD-related ILD.
  • Emerging techniques like ultrasound, MRI, and PET show promise in diagnosis and characterization.
  • Imaging findings are key to differentiating ILD subtypes and guiding treatment.

Conclusions:

  • Multidisciplinary approach and advanced imaging are vital for managing CTD-related ILD.
  • Understanding imaging findings aids in early detection and precise characterization of ILD in CTD patients.
  • Continued research into novel imaging techniques will enhance diagnostic capabilities for CTD-related ILD.