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Updated: Dec 10, 2025

Normothermic Negative Pressure Ventilation Ex Situ Lung Perfusion: Evaluation of Lung Function and Metabolism
Published on: February 14, 2022
Vapor for lung volume reduction; pros and cons
Paul Zarogoulidis1,2, Wolfgang Hohenforst-Schmidt3, Haidong Huang4
1Pulmonary Department, ``Bioclinic`` Private Hospital , Thessaloniki, Greece.
Bronchoscopic Vapor Thermal Ablation (BVTA) offers a safe, gradual approach for emphysema treatment. This editorial details BVTA, patient selection, and compares it with other lung volume reduction methods.
Area of Science:
- Pulmonology
- Interventional Pulmonology
- Medical Devices
Background:
- Emphysema management often involves lung volume reduction.
- Bronchoscopic Lung Volume Reduction (BLVR) is an evolving therapeutic strategy.
- Bronchoscopic Vapor Thermal Ablation (BVTA) is a specific BLVR technique.
Purpose of the Study:
- To provide a detailed overview of Bronchoscopic Vapor Thermal Ablation (BVTA).
- To discuss the safety, efficacy, and patient selection for BVTA.
- To compare BVTA with other minimally invasive BLVR modalities.
Main Methods:
- Editorial review of Bronchoscopic Vapor Thermal Ablation (BVTA).
- Discussion of clinical experience, including patient selection, procedure, and post-procedural care.
- Literature review comparing BVTA with endobronchial valves, coils, and lung sealants.
Main Results:
- BVTA is presented as an easy-to-perform and safe BLVR technique with gradual effects.
- Common side effects include pneumonitis and infection.
- Individualized patient assessment is crucial for optimal outcomes with BVTA.
Conclusions:
- BVTA is a promising, safe approach for lung volume reduction in emphysema.
- Further large-scale studies are required to establish BVTA as a standard treatment.
- BVTA offers a potentially safer alternative due to its gradual therapeutic effect.
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