Bacterial Cellulose: Functional Modification and Wound Healing Applications.

Area of Science:

• Biomaterials Science
• Regenerative Medicine
• Tissue Engineering

Background:

• Ideal wound dressings promote a moist environment and accelerate skin recovery.
• Bacterial cellulose (BC) is a natural biopolymer with advantageous properties for wound healing.

Purpose of the Study:

• To review the properties and modifications of bacterial cellulose for wound dressing applications.
• To highlight the potential of BC in promoting skin tissue regeneration.

Main Methods:

• Review of literature on bacterial cellulose synthesis and modification techniques.
• Analysis of BC's physicochemical and biological properties relevant to wound healing.
• Examination of BC-based wound dressing applications and clinical use.

Main Results:

• BC possesses a unique nanofiber network, high water retention, and mechanical strength.
• Various modification strategies (microbial, physical, chemical, compound) optimize BC's biocompatibility and antimicrobial efficacy.
• BC-based dressings demonstrate significant therapeutic effects in treating infected wounds, burns, and diabetic wounds.

Conclusions:

• Bacterial cellulose exhibits high clinical value as a wound dressing material.
• Its unique properties support its use in accelerating skin tissue regeneration.
• BC-based dressings are emerging as effective solutions in clinical practice for diverse wound types.