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Malignant Priapism - What Do We Know About It?

Dragos Marcu1,2, Lucian Iorga1, Dan Mischianu1,2,3

  • 1Clinic of Urology, University Emergency Central Military Hospital "Dr. Carol Davila", Bucharest, Romania.

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|September 3, 2020
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Summary
This summary is machine-generated.

Malignant priapism (MP) is rare, often linked to penile tumors or blood cancers. Hematological malignancies offer better survival rates for MP patients due to treatment sensitivity.

Keywords:
Malignant priapismhematological malignancypenile tumorsreview

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Area of Science:

  • Oncology
  • Urology

Background:

  • Malignancy is a rare cause of priapism.
  • Malignant priapism (MP) can result from primary penile tumors, metastatic penile tumors, or hematological malignancies.
  • Non-urological penile metastases are associated with a worse prognosis than urological ones, with priapism further worsening outcomes.

Purpose of the Study:

  • To review the role of malignancy in priapism pathogenesis.
  • To compare prognoses based on the origin of penile metastases and type of malignancy.
  • To outline management strategies for malignant priapism.

Main Methods:

  • Literature review of malignant priapism cases.
  • Analysis of prognostic factors including tumor origin and malignancy type.
  • Review of current therapeutic protocols for priapism and oncologic treatments.

Main Results:

  • Malignant priapism is uncommon, arising from various cancers.
  • Hematological malignancies associated with priapism show higher survival rates than non-hematological ones, owing to treatment sensitivity.
  • Most malignant priapism cases are ischemic.

Conclusions:

  • Malignant priapism requires a management approach similar to ischemic priapism, with added oncologic-specific treatments.
  • Prognosis varies significantly based on the type and origin of the malignancy.
  • Early recognition and tailored treatment are crucial for improving patient outcomes.