Related Experiment Video
Updated: Dec 10, 2025
Using Micro-computed Tomography for the Assessment of Tumor Development and Follow-up of Response to Treatment in a Mouse Model of Lung Cancer
Published on: May 20, 2016
Computed Tomography of Lymph Node Metastasis Before and After Radiation Therapy: Correlations With Residual Tumour
Naoya Ishibashi1, Toshiya Maebayashi2, Haruna Nishimaki3
1Department of Radiology, Nihon University School of Medicine, Tokyo, Japan ishibashi.naoya@nihon-u.ac.jp.
Background:
Computed tomography (CT) performed after radiation therapy (RT) is used to detect residual lymph node (LN) metastasis. Here, we investigated which LN parameters on pre- and post-RT CT images correlated with residual tumour in patients with head and neck cancer.
Patients And Methods:
We enrolled 23 patients who received RT. A total of 50 LNs were evaluated. Correlations between quantitative and qualitative findings and residual tumours were evaluated.
Results:
The median patient age was 61 years. Thirty-one LNs were histologically confirmed to contain residual tumour. LNs with residual tumour had significantly longer short and long axes on post-RT CT images. A new finding of obscured margins after RT were significantly associated with the presence of residual tumour by univariate and multivariate analyses.
Conclusion:
Comparison of qualitative, LN parameters on pre- and post-RT CT images may improve the detection of residual tumour in patients with suspected residual or recurrent LN metastasis.
