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Updated: Dec 10, 2025
Lung CT Segmentation to Identify Consolidations and Ground Glass Areas for Quantitative Assesment of SARS-CoV Pneumonia
Published on: December 19, 2020
Coronavirus disease 2019-associated rapidly progressive organizing pneumonia with fibrotic feature: Two case reports
Satoshi Okamori1, Ho Lee1, Yasushi Kondo2
1Division of Pulmonary Medicine.
Introduction:
Pneumonia is one of the most important characteristics of coronavirus disease 2019 (COVID-19) and imaging findings of COVID-19 pneumonia are diverse and change over disease course. However, the detailed clinical course of organizing pneumonia (OP) caused by COVID-19 has not been clarified.
Patient Concerns:
A 60-year-old man and a 61-year-old woman diagnosed with mild COVID-19 were admitted to our hospital. Their respiratory symptoms were deteriorating even after initiating treatment with antiviral drugs.
Diagnosis:
Chest X-rays and computed tomography scan showed a rapid progression of linear consolidation with reversed halo sign, distributed in subpleural and peri-bronchial regions. They also presented with pulmonary fibrosis findings, including traction bronchiectasis and marked lung volume reduction. They were diagnosed with rapidly progressing OP.
Interventions:
They were treated with systemic corticosteroids.
Outcomes:
The patients' imaging findings and respiratory conditions improved rapidly without any adverse effects.
Conclusion:
Physicians should carefully monitor patients with COVID-19, as they can develop rapidly progressive and fibrotic OP, which respond to corticosteroids.
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