Related Experiment Video For EBV
Updated: Dec 10, 2025

Isolation and Quantification of Epstein-Barr Virus from the P3HR1 Cell Line
Published on: September 28, 2022
Epstein-Barr Virus Mediated Signaling in Nasopharyngeal Carcinoma Carcinogenesis
Timmy Richardo1,2,3, Pongphol Prattapong4, Chawalit Ngernsombat4
1Institute of Virology, Hannover Medical School, 30625 Hannover, Germany.
Abstract:
Nasopharyngeal carcinoma (NPC) is one of the most common tumors occurring in China and Southeast Asia. Etiology of NPC seems to be complex and involves many determinants, one of which is Epstein-Barr virus (EBV) infection. Although evidence demonstrates that EBV infection plays a key role in NPC carcinogenesis, the exact relationship between EBV and dysregulation of signaling pathways in NPC needs to be clarified. This review focuses on the interplay between EBV and NPC cells and the corresponding signaling pathways, which are modulated by EBV oncoproteins and non-coding RNAs. These altered signaling pathways could be critical for the initiation and progression of NPC.
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