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Updated: Dec 10, 2025

Microvascular Embolism Mouse Model for In Vivo Two-photon Microscopy Using Fluorescent Polystyrene Microspheres
Published on: November 21, 2025
Blood flow diversion using the microvascular plug to avoid non target delivery of radioactive microspheres
Mohamed E Abdelsalam1, S Cheenu Kappadath2, Armeen Mahvash1
1Department of Interventional Radiology, The University of Texas MD Anderson Cancer Center, 1515 Holcombe Boulevard, Houston TX 77030-4009, USA.
Abstract:
Temporary balloon occlusion techniques have been described to redirect blood flow during hepatic chemo- and radioembolization. A 69 years old male with pathologically proven multifocal hepatocellular carcinoma involving all the liver segments except segments 2 and 3. We temporarily occlude segment 2/3 branch with the microvascular plug (MVP) to safely deliver the Y90 glass microspheres through the multiple small segment 4 branches. Distal occlusion using MVP may provide a valuable, cheaper and readily available tool in cases of unfavorable anatomy to divert blood flow and avoid non target delivery of Chemo or Radioembolic agents.

