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The epithelial-to-mesenchymal transition or EMT is a developmental process commonly observed in wound healing, embryogenesis, and cancer metastasis. EMT is induced by transforming growth factor-beta (TGF-β) or receptor tyrosine kinase (RTK) ligands, which further...
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Related Experiment Video

Updated: Dec 10, 2025

Spontaneous Murine Model of Anaplastic Thyroid Cancer
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Persistent Metastatic Thyroid Carcinoma.

Ghobad Azizi1, Michelle Lewis Mayo1, Yasmin Azizi1

  • 1Wilmington Endocrinology, PA, USA.

Journal of Medical Ultrasound
|September 3, 2020
PubMed
Summary
This summary is machine-generated.

Shear wave elastography (SWE) aids in assessing small thyroid nodules (TNs) and lymph nodes (LNs). This technique helps risk stratification for malignancy, guiding biopsy decisions and surgical extent.

Keywords:
Lymph nodeshear wave elastographythyroid carcinomathyroid noduleultrasound

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Area of Science:

  • Radiology
  • Oncology
  • Endocrinology

Background:

  • The decision to biopsy small thyroid nodules (TNs) remains challenging.
  • Ultrasound (US) and shear wave elastography (SWE) may improve risk stratification.
  • Evaluating cervical lymph nodes (LNs) is crucial for staging thyroid cancer.

Observation:

  • A 46-year-old female with hypothyroidism presented with small TNs.
  • A 4.8 mm left lobe TN was biopsied, confirming papillary thyroid carcinoma.
  • A suspicious left neck LN, unsampled due to vascular proximity, showed high velocity on SWE.

Findings:

  • SWE demonstrated high velocity in a suspicious LN, suggesting metastatic disease.
  • This case highlights the difficulty in risk stratifying small TNs and LNs.
  • SWE provided valuable information for malignancy risk assessment.

Implications:

  • SWE can enhance the diagnostic accuracy for small thyroid nodules.
  • This technique may influence the decision for fine needle aspiration biopsy.
  • SWE could guide surgical planning and extent in thyroid cancer management.