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Two mechanically ventilated cases of COVID-19 successfully managed with a sequential ventilation weaning protocol:
Mian Peng1, Di Ren2, Yong-Feng Liu3
1Department of Intensive Care Unit, The Third Affiliated Hospital of Shenzhen University, Shenzhen 518001, Guangdong Province, China.
World Journal of Clinical Cases
|September 3, 2020
Summary
A mechanical ventilation (MV) weaning protocol, including early prone positioning and infection control, may effectively manage critical COVID-19 patients with respiratory failure. This approach facilitated successful recovery in two severe cases.
Area of Science:
- Critical care medicine
- Infectious diseases
- Pulmonology
Background:
- Critical coronavirus disease 2019 (COVID-19) often leads to respiratory failure requiring mechanical ventilation (MV), posing a high mortality risk.
- Effective and practical MV weaning protocols are crucial for managing these vulnerable patients.
Observation:
- Two critical COVID-19 patients with respiratory failure initially received noninvasive ventilation (NIV) without improvement.
- Patients were advanced to MV with specific parameters, prone positioning, and comprehensive care including infection control and pharmacotherapy.
Findings:
- The described mechanical ventilation (MV) protocol involved early intubation/extubation, prone positioning, infection control, and sequential respiratory support withdrawal.
- Both patients successfully recovered after transitioning from MV through NIV and high-flow nasal cannula oxygen support.
Implications:
- This MV protocol may offer an effective strategy for managing critical COVID-19 patients.
- Optimizing intubation/extubation timing, early prone positioning, and phased respiratory support withdrawal are key components for successful weaning.
