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[Magnetic resonance study of renal function. Preliminary evaluation].

B Beomonte Zobel1, F Giammarile, P Di Renzi

  • 1Università degli Studi, Cattedra di Radiologia, l'Aquila.

La Radiologia Medica
|May 1, 1988
PubMed
Summary

Magnetic Resonance Imaging (MRI) can assess kidney function by measuring the cortico-medullary ratio (CMR). This MRI technique effectively monitors patients with chronic kidney disease.

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Area of Science:

  • Radiology
  • Nephrology

Background:

  • Assessing functioning renal parenchyma is crucial for managing kidney diseases.
  • Magnetic Resonance Imaging (MRI) offers a non-invasive method to evaluate kidney structure.

Purpose of the Study:

  • To evaluate the utility of MRI in estimating functioning renal parenchyma.
  • To correlate MRI-derived cortico-medullary ratio (CMR) and differentiation (CMD) with renal function and creatine blood levels.

Main Methods:

  • MRI scans were performed on 56 patients and 5 healthy volunteers using a 0.5 Tesla superconductive magnet system.
  • Spin-Echo pulse sequence (TR 300/TE 30 ms) was utilized to acquire kidney images.
  • Standardized cortico-medullary ratio (CMR) and differentiation (CMD) were calculated and compared with creatine blood levels.

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Main Results:

  • Cortico-medullary ratio (CMR) values ranged from 1.05 to 3.00, and CMD values ranged from 0.04 to 0.50.
  • Higher CMR and CMD values were observed in subjects with normal renal function, indicating good cortico-medullary contrast.
  • Patients with renal diseases exhibited lower CMR and CMD values, correlating with the severity of renal failure indicated by laboratory findings.

Conclusions:

  • MRI is a potentially useful technique for assessing the amount of functioning renal parenchyma.
  • The study suggests MRI can aid in the follow-up of patients with chronic renal disease by quantifying renal function.