Related Experiment Video
Updated: Dec 10, 2025

Assessment of Perigenital Sensitivity and Prostatic Mast Cell Activation in a Mouse Model of Neonatal Maternal Separation
Published on: August 13, 2015
Early Life Sexual Trauma and Later Life Genitourinary Dysfunction and Functional Disability in Women.
Pooja Lalchandani1, Nadra Lisha2, Carolyn Gibson3
1University of California, San Francisco, 1545 Divisadero Street, Box 0320, San Francisco, CA, 94143-0320, USA. Pooja.lalchandani@ucsf.edu.
Early sexual trauma in women is linked to long-term sexual dysfunction and functional decline in older age. Trauma-informed care is crucial for aging women
Area of Science:
- Gerontology
- Women's Health
- Trauma Studies
Background:
- Limited research exists on the long-term health consequences of early sexual trauma in older women.
- Previous studies focused on reproductive-aged women.
Purpose of the Study:
- To investigate the association between early life sexual trauma and later-life sexual/genitourinary dysfunction.
- To examine the link between early sexual trauma and general functional disability in older women.
Main Methods:
- Cross-sectional analysis of nationally representative data from the National Social Life, Health, and Aging Project (2010-2011).
- 1,745 US women aged 50 years and older were interviewed and surveyed.
- Assessed childhood sexual abuse, unwanted first sexual experiences, sexual/genitourinary dysfunction, and activities of daily living (ADL/IADL) limitations.
Main Results:
- Childhood sexual abuse was associated with increased odds of pain during sex, other urinary problems, and difficulties with multiple ADLs/IADLs.
- Unwanted first sexual experience was linked to reduced pleasure during sex and difficulties with certain ADLs/IADLs.
- Associations remained significant after adjusting for age, race, and education.
Conclusions:
- Early sexual trauma may serve as an under-recognized risk factor for functional decline in aging women.
- These findings highlight the necessity of trauma-informed care for women throughout their lifespan.
- Addressing past trauma is vital for supporting healthy aging in women.
Related Concept Videos
Nursing Assessment of the Genitourinary System I: Health History
Urinary Tract Infection II: Pathophysiology
Disorders of the Urinary System
Urinary tract infections (UTIs) are one of the most common urinary system disorders. They are caused by bacteria that enter the urethra and can spread to the bladder resulting in cystitis. Pyelonephritis is the result of a UTI that has ascended to the level of the...
Disorders of the Female Reproductive System
Disorders of the Male Reproductive System
Prostate disorders are another major concern. These conditions can impair urinary flow due to the prostate's location around the urethra....
Urinary Tract Calculi II: Pathophysiology and Clinical Manifestations

