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Updated: Dec 10, 2025

Semi-quantitative Detection of RNA-dependent RNA Polymerase Activity of Human Telomerase Reverse Transcriptase Protein
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Semi-quantitative Detection of RNA-dependent RNA Polymerase Activity of Human Telomerase Reverse Transcriptase Protein

Published on: June 12, 2018

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Telomerase RNA processing: Implications for human health and disease

Neha Nagpal1,2,3,4, Suneet Agarwal1,2,3,4

  • 1Division of Hematology/Oncology and Stem Cell Program, Boston Children's Hospital, Boston, Massachusetts, USA.

Stem Cells (Dayton, Ohio)
|September 3, 2020
PubMed
Summary

The human telomerase RNA component (TERC) is crucial for stem cell renewal and telomere maintenance. Disruptions in TERC biogenesis cause telomere biology disorders, offering insights into noncoding RNA diseases and potential therapies.

Keywords:
TERCTERTdyskeratosis congenitadyskerinnoncoding RNAstem cellstelomere

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